TY - JOUR ID - 49188 TI - Frequency of histological subtypes and patients’ survival with tumors originating from thymus JO - Jundishapur Journal of Oncology JA - JJO LA - en SN - 2423-6471 AU - Hosseini, Seyed Mohammad AU - Nezami, Ali Reza AU - Nezami, Puya AU - Razmjoo, Sasan AU - Arvandi, Sholeh AU - Shahbazian, Hodjatollah AD - Department of Radiotherapy and Oncology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran AD - Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran AD - Tehran University of Medical Sciences, Tehran, Iran Y1 - 2015 PY - 2015 VL - 1 IS - 2 SP - 3 EP - 8 KW - thymoma KW - Khuzestan KW - Metastase KW - Myasthenia gravis KW - Invasive thymoma DO - 10.22118/jjo.2015.49188 N2 - Background and Objective: Thymoma is a rare tumor in the mediastinum. Due to the fact that a complete study has not been conducted on thymoma in Khuzestan region, this study was designed as part of a comprehensive study on thymoma in Ahvaz Golestan Hospital.Materials and Methods: This retrospective study was conducted on patients’ medical records with Thymoma attending Department of Radiotherapy and Oncology, Ahvaz Golestan Hospital, in a 10-year period from 2001 to 2011. The study also aimed to investigate the epidemiological data; diagnosis and treatment of patients for the duration of the same time.Results: Among the 26 patients with a mean age of 45.38±SE, ratio of male to female was 5.5 to 1. The majority of the patients were in the range of 30-50 years old which jointly was at 61.8±SE. However, the minimum rate of tumor was seen in decades of 51-60 and 71-80 (7.7 %). In total, 72.7% (n=19) patients had invasive thymoma, while 27.3% (n=8) had noninvasive tumor. In addition, there was a significant relationship between invasive thymoma rate and developing myasthenia gravis. The 3-year survival rate for all patients was equivalent to 83.3%. However; 5-year survival was equal to 71%.Conclusions: According to the study, most patients with invasive thymoma had a 5-year survival rate and also most of them were with myasthenia gravis. UR - https://jjo.ajums.ac.ir/article_49188.html L1 - https://jjo.ajums.ac.ir/article_49188_cb8f351f2296fd3d07e04d64c8c1a4c2.pdf ER -