Unusual Metastatic Malignant Gastric Glomus Tumor (Glomangiosarcoma) : A case report and literature review

Document Type : Case Reports and Brief Reports


1 jundishapur univercity of medical sciences,ahvaz,iran

2 Department of Surgical Oncology, Cancer Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

3 Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran



Glomangioma (glomus tumor) is an
uncommon form of perivascular neoplasm
that from a clinical stand point is idle. It
appears from the glomus bodies,
arteriovenous anastomoses concerned with
thermoregulation. Glomus fibers
(specified pericytes) are transformed from
smooth muscle cells of the glomus body.
Glomangiosarcoma (malignant glomus
tumor) is an uncommon mesenchymal
sarcoma, responsible for less than 1% of
glomus neoplasms
They are discerned from the benign
counterpart by their spatial dimention
greater than 2.0cm, visceral or deep site,
infiltrative growth configuration ,and extra
histologic features. it has been stated that
glomangiosarcomas rarely metastatize.
We present a case of gastric glomus tumor
displaying malignant histologic
characteristics in a 67-year-old lady with
metastasis to liver and delayed metastasis to
thigh. Metastatic glomangiosarcomas,
particularly of the gastrointestinal tract, are
an uncommon entity and therefore clinical
manner of acting is ambiguous.
Hence, we executed a literature review of
over 110 articles to investigate and make
confidential this entity


Articles in Press, Accepted Manuscript
Available Online from 10 January 2021
  • Receive Date: 20 December 2020
  • Revise Date: 23 February 2024
  • Accept Date: 10 January 2021