Intestinal lymphoma presenting as intermittent bloody diarrhea and abdominal pain

Document Type : Case Reports and Brief Reports


1 Gastroenterologist, Research Center for Infectious Diseases of Digestive System, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

2 Fellowship of Gastroenterology, GI ward, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran


Background: Primary lymphoma of the colon is a rare tumor of the GI tract that comprises only 0.2-1.2% of all colonic malignancies and most commonly involve the cecum followed by the right colon and sigmoid. They can mimic features of ulcerative colitis and in this article we reporting a colonic lymphoma, which misdiagnosed as a refractory IBD.
Case Report: This is a middle- aged man presenting with abdominal pain and bloody diarrhea, which is diagnosed as ulcerative colitis, but due to the refractory symptoms and non-responsiveness, he has undergone further evaluation, which revealed the primary diffuse large B -cell lymphoma of the colon as the main culprit of patients’ symptoms and referred for systemic chemotherapy.
Conclusion: Colonic lymphomas can be presented as a mucosal type and characterized by small superficial erosive and hyperemic changes within a mucosal layer that can mimic the features of ulcerative colitis, so in any refractory IBD, their possibility should keep in mind.


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Volume 1, Issue 2 - Serial Number 2
December 2015
Pages 19-22
  • Receive Date: 05 October 2015
  • Revise Date: 01 November 2015
  • Accept Date: 18 November 2015
  • First Publish Date: 01 December 2015